簡(jiǎn)介:bis-peg9-acid is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
簡(jiǎn)介:bis-peg8-acid, a peg-based protac linker, is utilized in the synthesis of protacs and antibody-drug conjugates (adcs)[1]. it serves as a cleavable adc linker, facilitating the development of specialized compounds.
簡(jiǎn)介:mupirocin (brl-4910a) is a rna synthetase inhibitor antibacterial. it has shown excellent activity against gram-positive staphylococci and streptococci.
簡(jiǎn)介:bis-peg7-pfp ester is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
簡(jiǎn)介:bis-peg7-acid and bis-peg6-propionic acid are chemical compounds that serve as linkers in the synthesis of protacs and antibody-drug conjugates (adcs), respectively. bis-peg7-acid is a peg-based protac linker, while bis-peg6-propionic acid is a cleavable adc linker[1].
簡(jiǎn)介:bis-peg6-acid is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
簡(jiǎn)介:bis-peg5-pfp ester is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
簡(jiǎn)介:bis-peg5-acid (protac linker 36) is a polyethylene glycol (peg) linker employed for the synthesis of cp5v, a protac that selectively degrades cdc20[1].
簡(jiǎn)介:bis-peg4-sulfonic acid is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
簡(jiǎn)介:bis-peg4-pfp ester is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
簡(jiǎn)介:bis-peg3-sulfonic acid is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
簡(jiǎn)介:bis-peg3-pfp ester is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
簡(jiǎn)介:bis-peg3-acid is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
簡(jiǎn)介:bis-peg2-pfp ester is a non-cleavable 2-unit polyethylene glycol (peg) linker employed in the synthesis of antibody-drug conjugates (adcs) [1]. additionally, bis-peg2-pfp ester serves as a peg-based linker for the synthesis of proteolysis targeting chimeras (protacs) [2].
簡(jiǎn)介:bis-peg2-nhs ester, utilized in antibody-drug conjugation (adc), functions as a non-cleavable linker with two polyethylene glycol (peg) units.
簡(jiǎn)介:bis-peg2-acid is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
簡(jiǎn)介:bis-peg10-acid is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
簡(jiǎn)介:bis-peg1-pfp ester is a non-cleavable adc linker incorporating a 1-unit peg moiety, specifically designed for the synthesis of antibody-drug conjugates (adcs)[1].
簡(jiǎn)介:bis-peg1-acid is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
簡(jiǎn)介:bis-mal-peg3 is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.